人类

CDK1 - Cyclin Dependent Kinase 1

Alias:
CDC2
CDC28A
P34CDC2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是Ser/Thr蛋白激酶家族的成员。这个蛋白质是高度保守的蛋白激酶复合物M期促进因子(MPF)的催化亚单位,对于真核细胞周期的G1/S和G2/M期过渡是必不可少的。有丝分裂细胞周期蛋白稳定地与这个蛋白质结合并作为调节亚单位发挥作用。这个蛋白质的激酶活性受到细胞周期中细胞周期蛋白积累和破坏的控制。这个蛋白质的磷酸化和脱磷酸化也在细胞周期控制中起着重要的调节作用。已经发现这个基因的不同剪接转录变异体编码不同的异构体。[RefSeq,2009年3月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
6
8
16522 bp
34.09
3
--
14
61

CDK1 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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