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中文人类
ARHGAP11A - Rho GTPase Activating Protein 11A
Alias:
GAP (1-12)
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这个基因编码Rho GTP酶激活蛋白家族的一员。在响应DNA损伤时，编码的蛋白质与p53肿瘤抑制蛋白相互作用，并刺激其四聚化，从而导致细胞周期停滞和凋亡。包括这个基因的染色体缺失是Prader-Willi综合征的一个原因，这个基因的内含子变异可能与儿童的睡眠持续时间有关。这个基因在结肠癌症和人类基底样乳腺癌细胞系中高度表达。这个基因还产生ARHGAP11A-SCG5读穿转录本和ARHGAP11A-SCG5蛋白质。[由RefSeq，2019年2月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ARHGAP11A Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
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Mutations
Transcripts & Proteins
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Tile View
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Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Alphabetical
Cell-specific RNA expression
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References Literature
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