人类

KEAP1 - Kelch Like ECH Associated Protein 1

Alias:
INrf2
KLHL19
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个含有KELCH-1样结构域和BTB/POZ结构域的蛋白质。Kelch样ECH关联蛋白1以氧化还原敏感的方式与NF-E2相关因子2相互作用,并在细胞质中蛋白质的解离之后,将NF-E2相关因子2运输到细胞核中。这种相互作用导致γ-谷氨酰半胱氨酸合成酶的催化亚基的表达。已发现这个基因的两个可变剪接转录变异体,它们编码相同的异构体。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2
6
17232 bp
69.67
32
1
15
36

KEAP1 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
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