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中文人类
HDAC4 - Histone Deacetylase 4
Alias:
HD4
AHO3
BDMR
HDACA
HA6116
HDAC-4
HDAC-A
NEDCHF
NEDCHID
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组蛋白在转录调控、细胞周期进展和发育事件中起关键作用。组蛋白的乙酰化/去乙酰化改变染色体结构并影响转录因子访问DNA。此基因编码的蛋白质属于组蛋白去乙酰酶/acuc/apha家族的II类。它具有组蛋白去乙酰酶活性，当连接到启动子时抑制转录。此蛋白质不通过直接结合DNA，而是通过转录因子MEF2C和MEF2D。它似乎在RbAp48和HDAC3的多蛋白复合物中相互作用。[RefSeq,2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
HDAC4 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
