Home
Toolbox
Resource
Workflow
Tutorials
Citations
Downloads
Mutation Al-Predictor Flow
Gene-to-Mutation Flow
News & Insights
Genetic Encyclopedia
Frontiers
Industry Insights
Case Studies
About Us
About the Site
Contact Us
Private Policy
User Agreement
COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
Log In
|
Sign Up
中文
小鼠
Ptges2 - prostaglandin E synthase 2
Alias:
Gbf1
Pges2
Mpges2
0610038H10Rik
Create a favorites folder
Cancel
Confirm
Add To Favorites
Select a favorites
Description
New favorites >>
Cancel
Confirm
Favorite
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质是一个高尔基体膜关联的前列腺素E合酶候选物,能够在体外催化前列腺素H2转化为前列腺素E2。然而,使用缺乏该基因的小鼠的研究表明,这种酶并不参与前列腺素E2的体内生物合成。这种蛋白质作为高尔基体膜结合蛋白质合成,但在蛋白质成熟过程中其N端的疏水区域被切割掉,产生主要的可溶性的截断形式,仍保留酶活性。这种可溶性的蛋白质也被证明可以激活由γ-干扰素激活的转录因子(GATE)调控的转录,可能是通过与CAAAT/增强子结合蛋白-β的相互作用。[由RefSeq,2009年10月提供]
Related ID:
NCBI:96979
ENSEMBL:ENSMUSG00000026820
UNIPROT:Q8BWM0
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
96979
1
7
6851 bp
43.32
6
10
Ptges2 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Sequence
Comparison
Al agent
Tutorials
Back to top