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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
EIF5B - Eukaryotic Translation Initiation Factor 5B
Alias:
IF2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
真核生物中翻译的准确起始是复杂的,需要许多因子,其中一些因子由多个亚基组成。原核生物中的过程更简单,只有三个起始因子(IF1,IF2,IF3)。这些因子中的两个在真核生物中保守:IF1的同源物是eIF1A,IF2的同源物是eIF5B。这个基因编码eIF5B。eIF1A和eIF5B在核糖体上与其他起始因子和GTP相互作用,将起始甲硫氨酸tRNA定位在mRNA的起始密码子上,从而使翻译准确起始。[由RefSeq,2008年7月提供]
Related ID:
NCBI:9669
ENSEMBL:ENSG00000158417
HGNC:30793
UNIPROT:O60841
OMIM:606086
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
9669
1
24
63938 bp
138.83
38
--
3
26
EIF5B Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
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Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
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