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中文人类
CLCA2 - Chloride Channel Accessory 2
Alias:
CACC
CACC3
CLCRG2
CaCC-3
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这个基因编码一个钙激活氯通道调节器(CLCR)家族的蛋白质成员。这个家族的成员可以调节氯离子穿过质膜的运输。编码的蛋白质通过自蛋白酶解过程生成N-和C-端片段。这个基因的表达受到肿瘤抑制蛋白p53的上调，以应对DNA损伤。在乳腺癌中，这个基因的表达被下调，其编码的蛋白质可能抑制癌细胞系的迁移和侵袭，同时促进间质上皮转化。[RefSeq，2016年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CLCA2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
