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中文人类
RNF7 - Ring Finger Protein 7
Alias:
SAG
ROC2
rbx2
CKBBP1
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这个基因编码的蛋白质是一种高度保守的环指蛋白。它是SKP1-cullin/CDC53-F盒蛋白泛素连接酶的重要组成部分，这些连接酶是蛋白质降解机制的一部分，对于细胞周期进展和信号传导非常重要。这个蛋白质与酪蛋白激酶II(CSNK2A1/CKII)相互作用，并作为其底物。已经表明，CSNK2A1对这个蛋白质的磷酸化可以促进IkappaBalpha(CHUK/IKK-alpha/IKBKA)和p27Kip1(CDKN1B)的降解。已经报道了一种替代剪接转录变异体，编码不同的异构体。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
RNF7 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
