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中文人类
RNF14 - Ring Finger Protein 14
Alias:
ARA54
HFB30
TRIAD2
HRIHFB2038
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这个基因编码的蛋白质包含一个RING锌指结构，已知参与蛋白质-蛋白质相互作用。该蛋白质与雄激素受体（AR）相互作用，并可能作为协同激活因子，在前列腺中诱导AR靶基因的表达。已证实这个基因的显性负突变体可抑制前列腺癌的AR介导的生长。该蛋白质还与III类泛素结合酶（E2s）相互作用，并可能在某些核蛋白的泛素化中作为泛素结合酶（E3）发挥作用。已报道有六种可变剪接转录变异体，编码两种不同的异构体。[RefSeq，2011年1月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
RNF14 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
