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中文人类
BABAM2 - BRISC And BRCA1 A Complex Member 2
Alias:
BRE
BRCC4
BRCC45
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这个基因编码一种抗凋亡的、与死亡受体相关的蛋白质，可以与肿瘤坏死因子受体1相互作用。编码的蛋白质在包括BRCA1-A复合物和BRISC复合物在内的几个蛋白质复合物中作为适配器发挥作用。BRCA1-A复合物具有泛素酶活性，并靶向双链DNA断裂位点，而BRISC复合物具有去泛素酶活性，并涉及有丝分裂纺锤体组装。这个基因在几种癌症中上调。[RefSeq提供，2016年6月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
BABAM2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
