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中文人类
MACROH2A1 - MacroH2A.1 Histone
Alias:
H2A.y
H2A/y
H2AFY
mH2A1
H2AF12M
MACROH2A1.1
macroH2A1.2
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组蛋白是负责真核生物染色体纤维核小体结构的基本核蛋白质。核小体由约146bp的DNA围绕一组组蛋白八聚体组成，该八聚体由四种核心组蛋白（H2A、H2B、H3和H4）每对组成。通过连接蛋白H1与核小间DNA的相互作用，染色质纤维进一步压缩，形成更高阶的染色质结构。该基因编码一个复制独立的组蛋白，是组蛋白H2A家族的成员。它在一部分核小体中替换传统的H2A组蛋白，抑制转录并参与稳定的X染色体失活。可变剪接产生多种转录变异体，编码不同的异构体。[RefSeq，2015年10月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
MACROH2A1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
