人类

PTGES - Prostaglandin E Synthase

Alias:
PGES
MPGES
PIG12
PP102
PP1294
MGST-IV
MGST1L1
TP53I12
mPGES-1
MGST1-L1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是一种依赖谷胱甘肽的前列腺素E合酶。已有研究表明,这个基因的表达受到促炎细胞因子白介素1β(IL1B)的诱导。其表达还可以受到肿瘤抑制蛋白TP53的诱导,并可能涉及TP53诱导的凋亡。小鼠的敲除研究表明,这个基因可能参与胶原诱导的关节炎的病理发生,并在炎症反应过程中调节急性疼痛。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
3
14694 bp
17.10
10
--
9
16

PTGES Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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