Log In|Sign Up
中文人类
BAG3 - BAG Cochaperone 3
Alias:
BIS
MFM6
BAG-3
CAIR-1
Favorite
BAG蛋白质与Hip竞争结合Hsc70/Hsp70 ATP酶结构域，促进底物释放。所有BAG蛋白质在C端附近都有一个大约45个氨基酸的BAG结构域，但它们的N端区域差异很大。这个基因编码的蛋白质在N端区域含有WW结构域，在C端区域含有BAG结构域。BAG1、BAG2和BAG3的BAG结构域在体外和哺乳动物细胞中特异性地与Hsc70 ATP酶结构域相互作用。所有这三种蛋白质都以高亲和力与Hsc70的ATP酶结构域结合，并以Hip可抑制的方式抑制其分子伴侣活性。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
BAG3 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
