人类

AKAP5 - A-kinase Anchoring Protein 5

Alias:
H21
AKAP75
AKAP79
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
A-激酶锚定蛋白(AKAPs)是一组结构多样的蛋白质,它们共同的作用是结合蛋白激酶A(PKA)的调节亚基,并将全酶限制在细胞内的特定位置。这个基因编码AKAP家族的一员。编码的蛋白质结合PKA的RII-beta调节亚基,同时也结合蛋白激酶C和磷酸酶钙神经素。它主要在大脑皮质中表达,可能将PKA蛋白锚定在突触后密度(PSD)上,并参与突触后事件的调节。它也在T淋巴细胞中表达,可能通过破坏NFAT的钙神经素依赖性脱磷酸化来抑制白细胞介素-2的转录。[RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
2
9005 bp
47.09
23
--
11
7

AKAP5 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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