人类

ATG5 - Autophagy Related 5

Alias:
ASP
APG5
APG5L
hAPG5
SCAR25
APG5-LIKE
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质,与自噬蛋白12结合,作为泛素样结合系统中的E1样激活酶。该编码的蛋白质参与多种细胞过程,包括自噬囊泡形成、氧化损伤后的线粒体质量控制、先天抗病毒免疫应答的负调控、淋巴细胞发育和增殖、MHC II抗原呈递、脂肪细胞分化和凋亡。已发现这个基因的几个转录变异体编码不同的蛋白质异构体。[RefSeq,2015年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
8
8
141285 bp
32.45
9
1
8
26

ATG5 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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