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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
IL27RA - Interleukin 27 Receptor Subunit Alpha
Alias:
CRL1
TCCR
WSX1
IL27R
IL-27RA
zcytor1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
在老鼠中,CD4+辅助性T细胞可以分化成1型(Th1)细胞,这些细胞在细胞介导免疫中起关键作用,主要受IL12的影响。此外,IL4影响它们分化成2型(Th2)细胞,这些细胞在大多数抗体反应中起关键作用。这些细胞因子、它们的受体或相关的转录因子缺陷的小鼠,其Th1或Th2免疫反应受到损害,但并非完全缺失。这个基因编码一个在氨基酸水平上与小鼠T细胞细胞因子受体Tccr相似的蛋白质,并被预测是一个糖基化的跨膜蛋白。[由RefSeq,2008年7月提供]
Related ID:
NCBI:9466
ENSEMBL:ENSG00000104998
HGNC:17290
UNIPROT:Q6UWB1
OMIM:605350
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
9466
1
14
21457 bp
69.47
40
--
9
6
IL27RA Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Transcripts & Proteins
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Transcript
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CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
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Cell-specific RNA expression
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Type
Name
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Status
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References Literature
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