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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
PICK1 - Protein Interacting With PRKCA 1
Alias:
PICK
PRKCABP
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质包含一个PDZ结构域,通过这个结构域与蛋白激酶Cα(PRKCA)相互作用。这个蛋白质可能作为适配器,与多种膜蛋白的亚细胞定位结合和组织。已经证明它与多种谷氨酸受体亚型、单胺血浆膜转运蛋白以及非电压门控钠通道相互作用,可能使PRKCA定位到这些膜蛋白上,从而调节它们的分布和功能。这个蛋白质还被发现作为一种锚定蛋白质,以配体特异性的方式将PRKCA特异性地定位到线粒体上。已经发现这个基因有三个编码相同蛋白质的转录变异体。[由RefSeq,2008年7月提供]
Related ID:
NCBI:9463
ENSEMBL:ENSG00000100151
HGNC:9394
UNIPROT:Q9NRD5
OMIM:605926
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
9463
9
13
18447 bp
46.60
11
1
2
13
PICK1 Genetics information (+)
GRCh38
Sequence Homology
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* This data comes from NCBI.
Gene Expression
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