人类

PICK1 - Protein Interacting With PRKCA 1

Alias:
PICK
PRKCABP
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质包含一个PDZ结构域,通过这个结构域与蛋白激酶Cα(PRKCA)相互作用。这个蛋白质可能作为适配器,与多种膜蛋白的亚细胞定位结合和组织。已经证明它与多种谷氨酸受体亚型、单胺血浆膜转运蛋白以及非电压门控钠通道相互作用,可能使PRKCA定位到这些膜蛋白上,从而调节它们的分布和功能。这个蛋白质还被发现作为一种锚定蛋白质,以配体特异性的方式将PRKCA特异性地定位到线粒体上。已经发现这个基因有三个编码相同蛋白质的转录变异体。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
9
13
18447 bp
46.60
11
1
2
13

PICK1 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
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