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中文人类
ARHGEF6 - Rac/Cdc42 Guanine Nucleotide Exchange Factor 6
Alias:
PIXA
COOL2
MRX46
Cool-2
alphaPIX
alpha-PIX
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罗戈蛋白在由G蛋白偶联受体启动的细胞过程中发挥基本作用。该编码蛋白属于通过交换结合的GDP为GTP来激活Ras样Rho蛋白家族的胞质蛋白家族。它可以与G蛋白形成复合物并刺激Rho依赖的信号。该蛋白由PI3-激酶激活。该基因的突变可导致X染色体非特异性认知障碍。[RefSeq,2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ARHGEF6 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
