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中文人类
EIF2AK3 - Eukaryotic Translation Initiation Factor 2 Alpha Kinase 3
Alias:
PEK
WRS
PERK
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这个基因编码的蛋白质对真核翻译起始因子2的α亚基进行磷酸化，导致其失活，从而快速减少翻译起始并抑制全球蛋白质合成。这个蛋白质被认为可以调节线粒体功能。它是一种位于内质网（ER）的I型膜蛋白，当内质网应激由错误折叠的蛋白质引起时，它会受到诱导。这个基因的突变与Wolcott-Rallison综合征有关。[RefSeq，2015年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
EIF2AK3 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
