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中文人类
TNFRSF8 - TNF Receptor Superfamily Member 8
Alias:
CD30
Ki-1
D1S166E
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这个基因编码的蛋白质是肿瘤坏死因子受体超家族的一员。这个受体在激活的，但不在休息的T和B细胞中表达。TRAF2和TRAF5可以与这个受体相互作用，并介导导致NF-kappaB激活的信号转导。这个受体是细胞凋亡的正调节剂，也被证明可以限制自身反应性CD8效应T细胞的增殖潜力，并保护身体免受自身免疫的侵害。这个基因有两种可变剪接转录变体，编码不同的等位基因已被报道。[由RefSeq提供，2008年7月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TNFRSF8 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
