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中文人类
ABCG2 - ATP Binding Cassette Subfamily G Member 2 (Junior Blood Group)
Alias:
MRX
MXR
ABCP
BCRP
BMDP
MXR1
ABC15
BCRP1
CD338
GOUT1
MXR-1
CDw338
CDw388
UAQTL1
EST157481
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这个基因编码的膜关联蛋白属于ATP结合盒(ABC)转运蛋白超家族。ABC蛋白在细胞内外膜之间运输各种分子。ABC基因分为七个不同的亚家族(ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White)。这个蛋白是White亚家族的一员。它也被称为乳腺癌抵抗蛋白，具有异源污染物转运功能，可能在多药抗性中起主要作用。它可能作为细胞对米托蒽醌和蒽环类抗生素暴露的防御机制。这个蛋白在胎盘中的显著表达可能暗示了这个分子在胎盘组织中具有潜在作用。已经发现这个基因有多个转录变异体，编码不同的异构体。[RefSeq,2012年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ABCG2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
