人类

OPN4 - Opsin 4

Alias:
MOP
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
视蛋白是鸟嘌呤核苷酸结合蛋白(G蛋白)耦合受体超家族的成员。这个基因编码一种在视网膜神经节细胞和胺酸色素细胞层中表达的光感受器视蛋白。在鼠中,表达这个基因的视网膜神经节细胞的轴突延伸到视交叉上核和其他参与昼夜光适应的脑核。在鼠中,这个蛋白通过G蛋白信号通路耦合到瞬时受体电位(TRP)离子通道,并通过膜去极化和细胞内钙增加产生生理光反应。这个蛋白作为感光色素起作用,可能还具有光异构酶活性。用敲除鼠进行的实验表明,这个基因减弱,但不是消除,光适应。可变剪接产生多种编码不同异型体的转录变异体。[RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4
10
11914 bp
52.63
33
--
16
3

OPN4 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
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