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中文人类
CD86 - CD86 Molecule
Alias:
B70
B7-2
B7.2
LAB72
CD28LG2
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这个基因编码一种I型膜蛋白，属于免疫球蛋白超家族成员。这种蛋白由抗原呈递细胞表达，是T细胞表面两种蛋白的配体，即CD28抗原和细胞毒性T淋巴细胞相关蛋白4。这种蛋白与CD28抗原结合是T细胞激活的协同刺激信号。与细胞毒性T淋巴细胞相关蛋白4的结合负调节T细胞激活并减弱免疫反应。可变剪接产生几种编码不同异型体的转录变异体。[RefSeq提供，2011年5月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CD86 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
