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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Zfp423 - zinc finger protein 423
Alias:
Roaz
Ebfaz
nur12
Zfp104
Znf423
ataxia1
mKIAA0760
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有序列特异性的DNA结合活性。参与几个过程,包括Notch信号通路;负调控冷诱导产热;以及正调控BMP信号通路。在几个过程的上游或内部发挥作用,包括小脑颗粒细胞前体增殖;蛋白质定位到鞭毛;以及平滑化信号通路,参与小脑颗粒细胞前体细胞增殖的调控。位于细胞核中。在几个结构中表达,包括中枢神经系统;早期胎囊;胚胎外胚层;生殖泌尿系统;和感觉器官。用于研究Dandy-Walker综合征和小脑疾病。这个基因的人类同源物与肾结石14有关。与人类ZNF423(锌指蛋白423)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:94187
ENSEMBL:ENSMUSG00000045333
UNIPROT:Q80TS5
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
94187
9
8
300228 bp
145.35
21
15
Zfp423 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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