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中文人类
LPXN - Leupaxin
Alias:
LDPL
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这个基因编码的产物在造血细胞中优先表达，属于paxillin蛋白家族。与其他聚焦粘附相关适配器蛋白家族的成员相似，其在N端具有四个富含亮氨酸的LD结构域，在C端具有四个LIM结构域。它可能通过与PYK2（聚焦粘附激酶家族成员）结合，在细胞类型特异性的信号传导中发挥作用。作为淋巴细胞中酪氨酸激酶的底物，这种蛋白质也可能在酪氨酸激酶活性中发挥作用，并受到其调控。可变剪接产生多种编码不同异质体的转录变异体。[RefSeq，2009年1月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
LPXN Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
