人类

IGSF8 - Immunoglobulin Superfamily Member 8

Alias:
EWI2
PGRL
CD316
EWI-2
KCT-4
CD81P3
LIR-D1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码免疫球蛋白超家族中的EWI亚家族成员。这个家族的成员包含一个单一的跨膜结构域,一个EWI(Glu-Trp-Ile)基序和可变数量的免疫球蛋白结构域。这个蛋白质与四跨膜蛋白CD81和CD9相互作用,可能调节它们在某些细胞功能中的作用,包括细胞迁移和病毒感染。编码的蛋白质还可以通过抑制某些癌症的增殖来发挥肿瘤抑制因子作用。交替剪接产生多个转录变异体,它们编码相同的蛋白质。[由RefSeq,2011年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
10
7
8130 bp
65.03
36
--
7
11

IGSF8 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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