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中文人类
KLF4 - KLF Transcription Factor 4
Alias:
EZF
GKLF
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这个基因编码一个属于Kruppel家族转录因子的蛋白质。编码的锌指蛋白是皮肤屏障功能正常发育所必需的。编码的蛋白质被认为是通过调节肿瘤抑制基因p53来控制DNA损伤后的G1-S期细胞周期转换。缺乏这个基因的小鼠外观正常，但体重迅速减轻，并在出生后不久因皮肤屏障功能受损导致的液体蒸发而死亡。可变剪接产生多个编码不同异型体的转录本变异体。[由RefSeq，2015年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
KLF4 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
