人类

SOCS6 - Suppressor Of Cytokine Signaling 6

Alias:
CIS4
SSI4
CIS-4
SOCS4
STAI4
SOCS-4
SOCS-6
STATI4
HSPC060
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质包含一个SH2结构域和一个CIS同源结构域。因此,该蛋白质属于细胞因子诱导的STAT抑制剂(CIS),也称为细胞因子信号抑制子(SOCS)或STAT诱导的STAT抑制剂(SSI)蛋白质家族。CIS家族成员已知是细胞因子诱导的细胞因子信号的负调控因子。这个基因的表达可以在造血细胞中由GM-CSF和EPO诱导。在因子独立的慢性髓性白血病(CML)和红白血病(HEL)细胞系中,这个基因的高表达水平被发现在。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
10
2
41155 bp
59.53
13
--
3
4

SOCS6 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top