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中文人类
ATP6V1F - ATPase H+ Transporting V1 Subunit F
Alias:
VATF
Vma7
ATP6S14
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这个基因编码一个泡囊ATP酶（V-ATPase）的成分，这是一个调节真核细胞内器官酸化的多亚基酶。V-ATPase依赖的器官酸化对于诸如蛋白质分选、酶原激活、受体介导的内吞作用和突触囊泡质子梯度生成等细胞内过程是必要的。V-ATPase由细胞质V1结构和跨膜V0结构组成。V1结构由三个A和三个B亚基，两个G亚基以及C、D、E、F和H亚基组成。V1结构包含ATP催化位点。V0结构由五个不同的亚基组成：a、c、c'、c"和d。许多V1和V0亚基蛋白的额外异构体由多个基因或可选的剪接转录变体编码。这个编码的蛋白质是V1结构F亚基蛋白质。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ATP6V1F Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
