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中文人类
LGI1 - Leucine Rich Glioma Inactivated 1
Alias:
EPT
ETL1
ADLTE
ADPAEF
ADPEAF
IB1099
EPITEMPIN
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这个基因编码富含亮氨酸的重复序列（LRR）超家族的一员，并与SLIT蛋白家族的成员具有同源性。编码的蛋白质可能调节电压门控钾通道的活性，并可能参与神经元生长调控和细胞生存。这个基因在胶质母细胞瘤细胞系中由于易位而重排，并且在恶性胶质瘤中经常下调或重排。这个基因的突变导致常染色体显性侧颞叶癫痫。可选的剪接导致多个转录变异体。[由RefSeq，2015年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
LGI1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
