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中文人类
CD3E - CD3 Epsilon Subunit Of T-cell Receptor Complex
Alias:
T3E
TCRE
IMD18
CD3epsilon
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这个基因编码的蛋白质是CD3-epsilon多肽，与CD3-gamma、-delta和-zeta以及T细胞受体alpha/beta和gamma/delta异源二聚体一起形成T细胞受体-CD3复合物。这个复合物在将抗原识别与几个细胞内信号传导途径耦合中起着重要作用。编码epsilon、gamma和delta多肽的基因位于染色体11上的同一簇中。epsilon多肽在T细胞发育中起着基本作用。这个基因的缺陷导致免疫缺陷。这个基因也与女性患I型糖尿病的易感性有关。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CD3E Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
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CAS Number
Status
Phase
Link
References Literature
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PMID
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Year
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