人类

CCNE2 - Cyclin E2

Alias:
CYCE2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质属于高度保守的细胞周期蛋白家族,其成员的特点是蛋白质在细胞周期中的含量具有明显的周期性变化。细胞周期蛋白作为CDK激酶的调节因子发挥作用。不同的细胞周期蛋白表现出不同的表达和降解模式,这有助于有丝分裂事件的时序协调。这个细胞周期蛋白与CDK2形成复合物并作为其调节亚基发挥作用。这个细胞周期蛋白已被证明特异性地与CIP/KIP家族CDK抑制剂相互作用,并在细胞周期G1/S过渡中发挥作用。这个基因在G1-S期的表达达到高峰,并且表现出与细胞周期蛋白E1不同的组织特异性模式。在肿瘤衍生细胞中,这个基因的表达水平显著增加。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5
12
16470 bp
46.76
9
--
3
8

CCNE2 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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