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中文人类
DNAJA3 - DnaJ Heat Shock Protein Family (Hsp40) Member A3
Alias:
TID1
HCA57
hTID-1
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这个基因编码一个DNAJ/Hsp40蛋白家族的成员。DNAJ/Hsp40蛋白刺激Hsp70分子伴侣的ATP酶活性，并在蛋白质折叠、降解和多聚体复合体组装中起到关键作用。编码的蛋白质定位在线粒体上，并调节几个细胞过程，包括增殖、生存和凋亡信号传导。该编码蛋白还通过与包括ErbB2和p53肿瘤抑制蛋白在内的癌蛋白相互作用，在肿瘤抑制中起到关键作用。已经观察到这个基因的替代剪接转录变异体编码多个异构体。[RefSeq,2011年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
DNAJA3 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
