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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
PRC1 - Protein Regulator Of Cytokinesis 1
Alias:
ASE1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种参与细胞分裂的蛋白质。在细胞分裂的S期和G2/M期,该蛋白质水平较高,但当细胞从有丝分裂期退出并进入G1期时,其水平会急剧下降。在细胞周期中,它在核内定位,在有丝分裂过程中以高度动态的方式与有丝分裂纺锤体相关联,并在细胞分裂过程中定位到细胞中部。该蛋白质已被证明是几种细胞周期蛋白依赖的激酶(CDKs)的底物。它对于极化平行微管和集中负责收缩环组装的因子是必要的。选择性剪接导致多个转录变异体。[由RefSeq,2012年6月提供]
Related ID:
NCBI:9055
ENSEMBL:ENSG00000198901
HGNC:9341
UNIPROT:O43663
OMIM:603484
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
9055
33
15
28496 bp
71.61
48
--
5
23
PRC1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
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No data available
Transcripts & Proteins
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Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Type
Name
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CAS Number
Status
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Link
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References Literature
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