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中文人类
ARTN - Artemin
Alias:
ART
EVN
NBN
ENOVIN
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这个基因编码一种神经生长因子家族和转化生长因子β超家族的分泌配体。该家族配体结合各种转化生长因子β受体，导致SMAD家族转录因子的招募和激活，从而调节基因表达。编码的前体蛋白经过蛋白酶水解，生成二聚体中每个亚基。这种蛋白质通过RET受体和GFR alpha 3共受体信号，并支持许多周围神经元种群和至少一个中脑多巴胺神经元种群的生存。这种蛋白质还被证明可以促进乳腺癌的肿瘤生长、转移和药物抵抗。[由RefSeq提供，2016年8月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ARTN Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
