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中文人类
SOCS3 - Suppressor Of Cytokine Signaling 3
Alias:
CIS3
SSI3
ATOD4
Cish3
SSI-3
SOCS-3
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这个基因编码STAT诱导的STAT抑制剂(SSI)家族的一员，也被称为细胞因子信号抑制子(SOCS)家族。SSI家族成员是细胞因子信号的诱导性负调控因子。这个基因的表达受到各种细胞因子的诱导，包括IL6、IL10和干扰素(IFN)-γ。这个基因编码的蛋白质可以与JAK2激酶结合，并抑制JAK2激酶的活性。研究这个基因的鼠类对应物提示了这个基因在胎儿肝脏造血和胎盘发育的负调控中的作用。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SOCS3 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
