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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
TAX1BP1 - Tax1 Binding Protein 1
Alias:
T6BP
TXBP151
CALCOCO3
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个HTLV-1 tax1结合蛋白。编码的蛋白质与TNFAIP3相互作用,通过调节TNFAIP3的抗凋亡活性,抑制TNF诱导的凋亡。被类Caspase-3蛋白降解与该蛋白诱导的TNF凋亡有关。这个蛋白还可能具有抑制炎症信号通路的作用。已经发现这个基因的不同剪接转录变异体,它们编码不同的异构体。[RefSeq提供,2011年5月]
Related ID:
NCBI:8887
ENSEMBL:ENSG00000106052
HGNC:11575
UNIPROT:Q86VP1
OMIM:605326
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
8887
6
17
90395 bp
90.88
27
--
4
27
TAX1BP1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
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Mutations
No data available
Transcripts & Proteins
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Transcript
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CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
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Type
Name
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References Literature
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