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中文人类
SQSTM1 - Sequestosome 1
Alias:
p60
p62
A170
DMRV
OSIL
PDB3
ZIP3
p62B
NADGP
FTDALS3
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这个基因编码一个结合泛素并调节核因子kappa-B (NF-kB)信号通路活性的多功能蛋白。该蛋白作为支架/适配器蛋白与TNF受体相关因子6协同作用，以响应上游信号来调节NF-kB的激活。已经在这个基因中鉴定出编码相同或不同异构体的可变剪接转录变异体。这个基因的突变导致骨斑疹性熟病和家族性斑疹性熟病。[RefSeq,2009年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SQSTM1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
