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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
VNN1 - Vanin 1
Alias:
HDLCQ8
Tiff66
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码vanin家族蛋白质的一员,这个家族的蛋白质与其他成员以及生物素酶有广泛的序列相似性。这个家族包括分泌的和膜关联的蛋白质,其中一些已经报道参与造血细胞的迁移。然而,任何vanin蛋白质都没有显示出生物素酶活性,但它们具有泛硫酶活性,这可能在与氧化应激反应中发挥作用。这个蛋白质,就像它的小鼠同系物一样,可能是一个GPI锚定的细胞表面分子。小鼠蛋白质由胸腺基质细胞的周缘表达,并调节T细胞祖细胞向胸腺的迁移。这个基因位于染色体6q23-q24上的其他两个vanin基因附近,并且与它们有相同的转录方向。[由RefSeq,2009年2月提供]
Related ID:
NCBI:8876
ENSEMBL:ENSG00000112299
HGNC:12705
UNIPROT:O95497
OMIM:603570
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
8876
1
7
33207 bp
57.01
34
--
7
11
VNN1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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Cell-specific RNA expression
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Name
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Status
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References Literature
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