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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
PER2 - Period Circadian Regulator 2
Alias:
FASPS
FASPS1
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Description
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因是Period家族基因的一员,在哺乳动物大脑中的主要生物钟调谐器视交叉上核中以日周期模式表达。这个家族的基因编码运动活性、代谢和行为日节律的成分。这个基因被CLOCK/ARNTL异源二聚体上调,然后通过使用与CLOCK/ARNTL相互作用的PER/CRY异源二聚体在反馈回路中抑制这种上调。这个基因的多态性可能增加患某些癌症的风险,并与睡眠障碍有关。[由RefSeq,2014年1月提供]
Related ID:
NCBI:8864
ENSEMBL:ENSG00000132326
HGNC:8846
UNIPROT:O15055
OMIM:603426
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
8864
5
23
56022 bp
136.58
87
2
22
13
PER2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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