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中文人类
PROZ - Protein Z, Vitamin K Dependent Plasma Glycoprotein
Alias:
PZ
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这个基因编码一种在肝脏中合成的维生素K依赖的糖蛋白，并在血浆中分泌。编码的蛋白质通过与蛋白质Z依赖的蛋白酶抑制剂复合物作用，在磷脂表面直接抑制激活的因子X，从而在调节血液凝固中发挥作用。该蛋白质的缺乏与缺血性动脉疾病的风险增加和胎儿丢失有关。该基因中的突变是导致蛋白质Z缺乏的原因。交替剪接导致多个转录变异体。[RefSeq，2012年1月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PROZ Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
