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中文人类
NR1I2 - Nuclear Receptor Subfamily 1 Group I Member 2
Alias:
BXR
PAR
PRR
PXR
SAR
SXR
ONR1
PAR1
PAR2
PARq
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这个基因产物属于核受体超家族，其成员是特征明显的转录因子，具有配体结合域和DNA结合域。编码的蛋白质是细胞色素P450基因CYP3A4的转录调节因子，作为与9-顺式视黄酸受体RXR的异源二聚体，结合到CYP3A4启动子的响应元素上。它由一系列诱导CYP3A4的化合物激活，包括地塞米松和利福平。已经描述了这个基因的几个可变剪接转录本，编码不同的异构体，其中一些使用非AUG（CUG）翻译起始密码子。然而，还存在其他转录变异体，但它们尚未完全特征化。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
NR1I2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
