人类

NRP1 - Neuropilin 1

Alias:
NP1
NRP
BDCA4
CD304
VEGF165R
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这种基因编码两种神经丝之一,它们含有特定的蛋白质结构域,使它们能够参与几种不同类型的信号传导途径,从而控制细胞迁移。神经丝包含一个大型N端细胞外结构域,由补体结合、凝血因子V/VIII和meprin结构域组成。这些蛋白质还包含一个短的膜穿透结构域和一个小的胞质结构域。神经丝结合许多配体和各种类型的共受体;它们影响细胞的生存、迁移和吸引力。神经丝结合的一些配体和共受体是血管内皮生长因子(VEGF)和semaphorin家族成员。该蛋白质还被确定为SARS-CoV-2(导致COVID-19的病毒)的共受体,以感染宿主细胞。[由RefSeq,2020年11月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
17
17
157175 bp
103.13
69
--
14
22

NRP1 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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