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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
CES2 - Carboxylesterase 2
Alias:
iCE
CE-2
PCE-2
CES2A1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码羧酸酯酶大家族的一员。这个家族的成员负责水解或转移各种外源性物质,如可卡因和海洛因,以及具有酯、硫酯或酰胺键的内源性底物。它们可能参与脂肪酸和胆固醇酯的代谢,并在血脑屏障系统中发挥作用。这个基因编码的蛋白质是主要的肠道酶,并在肠道药物清除中发挥作用。已经发现这个基因的替代剪接转录变异体。[RefSeq,2010年10月提供]
Related ID:
NCBI:8824
ENSEMBL:ENSG00000172831
HGNC:1864
UNIPROT:O00748
OMIM:605278
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
8824
6
12
10626 bp
61.81
21
--
19
14
CES2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
Table View
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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