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中文人类
DPM2 - Dolichyl-phosphate Mannosyltransferase Subunit 2, Regulatory
Alias:
CDG1U
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道尔基醇-磷酸甘露糖（Dol-P-Man）作为内质网（ER）腔侧甘露糖残基的供体。缺乏Dol-P-Man导致GPI锚定蛋白的表面表达缺陷。Dol-P-Man由ER细胞质侧的道尔基醇-磷酸甘露糖基转移酶从GDP-甘露糖和道尔基醇-磷酸酯中合成。这个基因编码的蛋白质是一个含有2个预测的跨膜结构域和在C端附近的ER定位信号的疏水蛋白质。这个蛋白质在活体内与DPM1结合，并且是DPM1的ER定位和稳定表达所必需的，同时增强道尔基醇-磷酸酯与DPM1的结合。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
DPM2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
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Tile View
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Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
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Abundance
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Interactions
Acting
Regulation
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Name
MGI
Strain of Origin
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Link
References Literature
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