人类

IL18R1 - Interleukin 18 Receptor 1

Alias:
CD218a
IL18RA
IL1RRP
CDw218a
IL-1Rrp
IL-18Ralpha
IL18Ralpha2
IL-18R-alpha
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是一种属于白细胞介素1受体家族的细胞因子受体。这个受体特异地结合白细胞介素18(IL18),并且对于IL18介导的信号传导是必不可少的。据报道,IFN-alpha和IL12能够诱导NK细胞和T细胞中这个受体的表达。这个基因与白细胞介素1受体家族的四个其他成员(包括IL1R2、IL1R1、ILRL2(IL-1Rrp2)和IL1RL1(T1/ST2))一起,在染色体2q上形成一个基因簇。已经发现这个基因的不同剪接转录变异体编码不同的异构体。[由RefSeq,2013年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
15
11
42981 bp
62.30
16
--
6
11

IL18R1 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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