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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
RGS11 - Regulator Of G Protein Signaling 11
Alias:
RS11
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质属于RGS(G蛋白信号调节子)家族。RGS家族的成员作为异源三聚G蛋白的信号传导G蛋白α亚基的GTP酶激活蛋白。这个蛋白质通过增加G蛋白α亚基的GTP酶活性来抑制信号传导,从而驱动它们进入其失活的GDP结合形式。在这个位置发生可选的剪接,并且已经发现了四种编码不同异构体的转录变异体。[由RefSeq,2013年11月提供]
Related ID:
NCBI:8786
ENSEMBL:ENSG00000076344
HGNC:9993
UNIPROT:O94810
OMIM:603895
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
8786
12
17
7638 bp
52.95
30
--
2
6
RGS11 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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