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中文人类
TNFRSF18 - TNF Receptor Superfamily Member 18
Alias:
AITR
GITR
CD357
GITR-D
ENERGEN
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这个基因编码TNF受体超家族的一个成员。编码的受体在T细胞激活后已显示有增加的表达，被认为在CD25(+)CD4(+)调节性T细胞维持的主导免疫自耐受中起关键作用。小鼠的敲除研究也表明该受体在调节CD3驱动的T细胞激活和程序性细胞死亡中的作用。已报告了该基因的三种可变剪接转录变体，编码不同的等位基因。[由RefSeq提供，2011年2月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TNFRSF18 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
