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中文人类
SIGLEC5 - Sialic Acid Binding Ig Like Lectin 5
Alias:
CD170
OBBP2
CD33L2
OB-BP2
SIGLEC-5
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这个基因编码唾液酸结合免疫球蛋白样凝集素（Siglec）家族的一员。这些细胞表面凝集素的特点是在免疫球蛋白（Ig）样结构域中的结构基序和第一个Ig V集结构域中的唾液酸识别位点。编码的蛋白质是Siglec中与CD33相关的子集成员，并抑制包括单核细胞、巨噬细胞和中性粒细胞在内的几种细胞的激活。B组链球菌（GBS）与编码蛋白的结合在GBS免疫逃逸中起作用。[RefSeq，2012年2月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SIGLEC5 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
