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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
TNFSF13 - TNF Superfamily Member 13
Alias:
APRIL
CD256
TALL2
ZTNF2
TALL-2
TNLG7B
TRDL-1
UNQ383/PRO715
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是肿瘤坏死因子(TNF)配体家族的成员。这种蛋白质是TNFRSF17/BCMA的配体,属于TNF受体家族。这种蛋白质及其受体对B细胞发育都很重要。体外实验表明,这种蛋白质可能能够通过与其他TNF受体家族蛋白质如TNFRSF6/FAS和TNFRSF14/HVEM的相互作用来诱导凋亡。可变剪接产生了多种转录子变异体。已经发现了跳过上游基因(TNFSF12)最后一个外显子并继续进入这个基因的第二个外显子的某些转录本;这种读穿转录本包含在GeneID 407977,TNFSF12-TNFSF13中。[由RefSeq,2010年10月提供]
Related ID:
NCBI:8741
ENSEMBL:ENSG00000161955
HGNC:11928
UNIPROT:O75888
OMIM:604472
Basic Information
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8741
6
6
3320 bp
27.43
13
--
6
12
TNFSF13 Genetics information (+)
GRCh38
Sequence Homology
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* This data comes from NCBI.
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